I work at a University where we have 250+ lab computers. We use mandatory user profiles (stored on a Windows Server 2008 - Domain Controller) and have recently migrated to Windows 7 on all our lab computers. About two weeks after we went to Windows 7 we started encountering the error; "User Profile Service service failed the logon User profile service cannot be loaded". This happens when booting the computers and trying to log in as the mandatory user (Student) which I created from scratch for Windows 7. The problem occurs on about half the computers (random computers) every morning. To temporarily fix this when it happens, I log in as a Domain Admin user and go into Advance System Settings -> User Profiles -> Settings and delete the local copy of the mandatory user "Student" . I then log out and log in as "Student" and it works fine for the day. Also the problem has occurred when logging on as other mandatory accounts other than "Student". I have not experienced the problem when logging in with accounts that are not mandatory (i.e. roaming profile accounts or local accounts). Does anyone have a clue as to why this is a continuing problem, and/or what could be done to fix it permanently? It take me and my staff an hour a day just to turn on computers....not cool at all.