Afert a Reboot or Startup, my usb devices are not active, my usb external hd, tablet pen device, flash drives, etc have to be plugged out and in again to be seen by windows.Any ideas?

Can you recall when the issue began to occur?If the trouble just happened recently, you can try system restore. If not, you'd better to update your drivers, such as BIOS, Chipset driver and tablet pen device from the manufacture. In addition, you can test you issue in the Clean boot mode. Good luck!John

Hi marius82, Please first try John's suggestions to check this issue. For the detailed steps about Clean Boot, please refer to this knowledge base (KB) article: How to troubleshoot a problem by performing a clean boot in Windows Vista or in Windows 7. If the issue persists, please move on to reinstall the USB controllers by the steps below to check the result: Use the Mouse ================ First, please disconnect all USB devices and then perform the following steps: 1. Click "Start" button, type “devmgmt.msc” (without quotation marks) in the “Search” bar and press "Enter". Click “Continue” if necessary. 2. In Device Manager, double click to expand "Universal Serial Bus controllers", right click on the Host Controller, click "Uninstall" and click "OK". 3. Repeat the step 2 to uninstall all items under "Universal Serial Bus controllers". Then, restart your computer and Windows 7 will reinstall all USB controllers automatically. Use the Keyboard ================ First, please disconnect all USB devices. Then, go through the following steps: 1. Press "Ctrl + Esc" to open the “Start” menu. 2. Type “devmgmt.msc” in the Search bar and press "Enter". Click “Continue” if necessary. 3. In Device Manger, press Tab and use "Up" and "Down" to move the highlight to "Universal Serial Bus Controllers". 4. Press "Right" and expand it. 5. Press "Down" to move to the first item and press "Delete" to remove it. 6. Repeat the step 5 and uninstall all items under "Universal Serial Bus Controllers". Then, restart your computer and Windows 7 will reinstall all controllers automatically. Hope this helps. Regards, Linda