I swear I have done everything to solve this problem. I've spent the last 6+ hours since I was an idiot and downloaded from somewhere I didn't really trust trying to solve this problem. I doubt anyone will be able to help me aside from telling me to format my drive, but here goes. It all started when I downloaded a file and ran it as administrator. As soon as I did the file disappeared from the desktop and I knew bad things were about to happen. Microsoft Security Essentials popped up and said that some files were installed that might be bad but it didn't know so it wanted permission to send them off to be reviewed. So I gave permission then immediately went to where the files were saved and deleted them, but while I was doing this I could see other files start popping up in the same location. I couldn't tell exactly which files they were though, I just saw the files scrolling around. I could have gone and deleted everything that was modified at that time, but I was afraid that the virus may have infected something essential and that I would kill my computer. So after that I ran MSE and no threats were found. I then ran the free version of Malwarebytes and it found 5 security threats, a few trojans, something that said faketrojan or something to that extent. I quarantined and then deleted them all. Malwarebytes then prompted me to restart the computer to make sure everything was completely removed so I did. When I came back everything seemed fine for a few minutes but then I got the little problem popup in the bottom right saying that the security center was turned off, defender was turned off, and I had no antivirus. I immediately started up MSE but it popped up for a few seconds with the red theme (showing that it is turned off) and then went away. I tried again and again and every time it did the same thing. When I went to the icons on the toolbar in the bottom right as soon as I moved my mouse over the MSE icon it disappeared. I thought this must be some trace of the virus that is preventing me from opening MSE so I can't get rid of it, so I ran another scan with Malwarebytes but it found nothing. I thought that there may have been some damage to the program from the virus so I uninstalled MSE and reinstalled, but the problem persisted. Next, I downloaded the free 30 day trial of Kaspersky Antivirus 2011 and ran a complete scan with that which found nothing. After much more searching on the internet someone described having the same problem and said that booting into safe mode allowed them to run MSE which found the virus that stopped it from loading in normal mode and the problem was solved. So that's what I did. I booted into safe mode and just like the person said, MSE was able to start so I ran a complete scan. It found nothing. I then ran a complete scan with Malwarebytes in safe mode and it found nothing. I then ran a complete scan with Kaspersky in safe mode and it found nothing. I did some more searches and found a link to a complete wscsvc registry file, which someone claimed was the problem and that it would fix it. There were several other people praising the person after this saying that it solved the problem, so I made a backup of wscsvc and imported the new one. It didn't do any harm, but it also didn't solve the problem. I searched around some more and found that some people said that the popups only affect one user and that it could be the result of the user being corrupt as a result of damage from the virus. So I created a new administrative account, logged out of my account, logged into the new one, uninstalled MSE, reinstalled it, tried to run it, and again it would disappear within seconds. I also continued getting the popup messages and was still unable to start the security center. I deleted the new account and went back to my original, ran CCleaner registry error sweep out of pure desperation, it found some problems, I fixed them, the problem is still there. Oh and somewhere along the way I went to services and changed security center and defender to automatic (also tried Automatic with delay) along with apply and then start and ok, and it said automatic on the list after that and looked like it worked, but it never really opened, and when I checked on it later it said disabled again. I also ran the Kaspersky rootkit killer and it returned no results. I also ran sfk /scannow twice and both times it said there were no problems. So here I am, having tried everything short of formatting my drive that I haven't backed up with very important files (I can't afford an external drive at the moment). Formatting is not an option. Internet searches have stopped yielding possible solutions. Can anyone help? Please? UPDATE: Deleted temporary files, problem continues. Ran avast full scan - found nothing. Ran avast boot scan - found some corruptions but no infections. I took care of the corruptions. Ran AVG full scan - found nothing. Ran AVG rootkit scan - found nothing. Ran AVG PC Tuneup fixed registry errors, fragmentation, etc. Problem continues. All of the top anti-virus/malware/spyware is telling me there's nothing, but something must be killing MSE when it starts. I just don't understand it. After all of this my computer should be completely clean.