Hi GSSourse,
Do you mean that you want to add a remote RADIUS server to authenticate for the network access server? Radius clients are network access servers, such as wireless access points, 802.1X-capables switch, VPN servers, and dial-up servers. Client computers, such as wireless portable computers cant be RADIUS clients.
If my understanding is right that you would like to use a remote RADIUS server to authenticate for the network access server, you can refer to the following documents
RADIUS server for 802.1X wireless or wired connections:
https://technet.microsoft.com/en-us/library/cc731853(v=ws.10).aspx
RADIUS server for dial-up or VPN connections
https://technet.microsoft.com/en-us/library/cc731108(v=ws.10).aspx
Some reference about NPS:
https://technet.microsoft.com/en-us/library/dd197558(v=ws.10).aspx
Besides, when you have configured the RADIUS server and the network access server correctly, they can communicate with each other, no matter they are in the same subnet or not.
Best Regards,