Does anyone know if Microsoft has a tool for changing the MSDTC GUID on a server. This is a Windows 2012 server. We cloned a Biztalk server for production purposes and MSDTC has the GUID of the clone. Tried the uninstall route and removing entries from registry. it will not resinstall because the GUID matches another machine.

You have to uninstall and then install MSDTC again (or you could go the wild path and just set another GUID). Uninstalling/installing MSDTC is done via the command prompt.

• Use Add Windows Components, and remove Network DTC.       

• Go to the command line and run: MSDTC -uninstall       

• Go to the registry and delete the MSDTC keys in HKLM/Software/Microsoft/Software/MSDTC, HKLM/System/CurrentControlSet/Services/MSDTC, and HKEYCLASSESROOTCID (if they're still there).       

• Reboot       

• Go to the command line and run: MSDTC -install       

• Use Add Windows Components, and add Network DTC.       

• Go to the command line and run: net start msdtc.

• Refer: http://www.wadewegner.com/2007/08/warning-the-cid-values-for-both-test-machines-are-the-same/

•  http://www.captechconsulting.com/blogs/cloning-a-biztalk-development-server

From a command prompt run msdtc -uninstall without the quotes.

1. Verify the DTC was uninstalled successfully by reviewing the application event log.
2. Open regedit and ensure the following registry keys have been deleted (they all may not be present):
   • HKEY_CLASSES_ROOT\CID
   • HKEY_CLASSES_ROOT\CID.Local for Windows 2008
   • HKEY_LOCAL_MACHINE\SOFTWARE\Microsoft\MSDTC
   • HKEY_LOCAL_MACHINE\SYSTEM\CurrentControlSet\Services\MSDTC
3. Reboot the Server
4. From a command prompt run msdtc -install without the quotes.
5. Verify the MSDTC was installed successfully by reviewing the application event log.
6. From a command prompt run msdtc -resetlog without the quotes.
7. In the Administrative tools, Services verify the Distributed Transaction Coordinator service is started and then change the properties of the service so the start up type is automatic.
8. Enable DTC network access if required.

For Reference below MSDN blog will be helpfull 

http://blogs.msdn.com/b/distributedservices/archive/2009/04/01/instructions-to-reinstall-the-microsoft-distributed-transaction-coordinator-msdtc-service.aspx

Thanks
Abhishek

From a command prompt run msdtc -uninstall without the quotes.

1. Verify the DTC was uninstalled successfully by reviewing the application event log.
2. Open regedit and ensure the following registry keys have been deleted (they all may not be present):
   • HKEY_CLASSES_ROOT\CID
   • HKEY_CLASSES_ROOT\CID.Local for Windows 2008
   • HKEY_LOCAL_MACHINE\SOFTWARE\Microsoft\MSDTC
   • HKEY_LOCAL_MACHINE\SYSTEM\CurrentControlSet\Services\MSDTC
3. Reboot the Server
4. From a command prompt run msdtc -install without the quotes.
5. Verify the MSDTC was installed successfully by reviewing the application event log.
6. From a command prompt run msdtc -resetlog without the quotes.
7. In the Administrative tools, Services verify the Distributed Transaction Coordinator service is started and then change the properties of the service so the start up type is automatic.
8. Enable DTC network access if required.

For Reference below MSDN blog will be helpfull 

http://blogs.msdn.com/b/distributedservices/archive/2009/04/01/instructions-to-reinstall-the-microsoft-distributed-transaction-coordinator-msdtc-service.aspx

Thanks
Abhishek

• Marked as answer by Angie xuMicrosoft contingent staff, Moderator 1 hour 36 minutes ago

From a command prompt run msdtc -uninstall without the quotes.

1. Verify the DTC was uninstalled successfully by reviewing the application event log.
2. Open regedit and ensure the following registry keys have been deleted (they all may not be present):
   • HKEY_CLASSES_ROOT\CID
   • HKEY_CLASSES_ROOT\CID.Local for Windows 2008
   • HKEY_LOCAL_MACHINE\SOFTWARE\Microsoft\MSDTC
   • HKEY_LOCAL_MACHINE\SYSTEM\CurrentControlSet\Services\MSDTC
3. Reboot the Server
4. From a command prompt run msdtc -install without the quotes.
5. Verify the MSDTC was installed successfully by reviewing the application event log.
6. From a command prompt run msdtc -resetlog without the quotes.
7. In the Administrative tools, Services verify the Distributed Transaction Coordinator service is started and then change the properties of the service so the start up type is automatic.
8. Enable DTC network access if required.

For Reference below MSDN blog will be helpfull 

http://blogs.msdn.com/b/distributedservices/archive/2009/04/01/instructions-to-reinstall-the-microsoft-distributed-transaction-coordinator-msdtc-service.aspx

Thanks
Abhishek

• Marked as answer by Angie xuMicrosoft contingent staff, Moderator Tuesday, July 14, 2015 5:29 AM

From a command prompt run msdtc -uninstall without the quotes.

1. Verify the DTC was uninstalled successfully by reviewing the application event log.
2. Open regedit and ensure the following registry keys have been deleted (they all may not be present):
   • HKEY_CLASSES_ROOT\CID
   • HKEY_CLASSES_ROOT\CID.Local for Windows 2008
   • HKEY_LOCAL_MACHINE\SOFTWARE\Microsoft\MSDTC
   • HKEY_LOCAL_MACHINE\SYSTEM\CurrentControlSet\Services\MSDTC
3. Reboot the Server
4. From a command prompt run msdtc -install without the quotes.
5. Verify the MSDTC was installed successfully by reviewing the application event log.
6. From a command prompt run msdtc -resetlog without the quotes.
7. In the Administrative tools, Services verify the Distributed Transaction Coordinator service is started and then change the properties of the service so the start up type is automatic.
8. Enable DTC network access if required.

For Reference below MSDN blog will be helpfull 

http://blogs.msdn.com/b/distributedservices/archive/2009/04/01/instructions-to-reinstall-the-microsoft-distributed-transaction-coordinator-msdtc-service.aspx

Thanks
Abhishek

• Marked as answer by Angie xuMicrosoft contingent staff, Moderator Tuesday, July 14, 2015 5:29 AM

From a command prompt run msdtc -uninstall without the quotes.

1. Verify the DTC was uninstalled successfully by reviewing the application event log.
2. Open regedit and ensure the following registry keys have been deleted (they all may not be present):
   • HKEY_CLASSES_ROOT\CID
   • HKEY_CLASSES_ROOT\CID.Local for Windows 2008
   • HKEY_LOCAL_MACHINE\SOFTWARE\Microsoft\MSDTC
   • HKEY_LOCAL_MACHINE\SYSTEM\CurrentControlSet\Services\MSDTC
3. Reboot the Server
4. From a command prompt run msdtc -install without the quotes.
5. Verify the MSDTC was installed successfully by reviewing the application event log.
6. From a command prompt run msdtc -resetlog without the quotes.
7. In the Administrative tools, Services verify the Distributed Transaction Coordinator service is started and then change the properties of the service so the start up type is automatic.
8. Enable DTC network access if required.

For Reference below MSDN blog will be helpfull 

http://blogs.msdn.com/b/distributedservices/archive/2009/04/01/instructions-to-reinstall-the-microsoft-distributed-transaction-coordinator-msdtc-service.aspx

Thanks
Abhishek

• Marked as answer by Angie xuMicrosoft contingent staff, Moderator Tuesday, July 14, 2015 5:29 AM

From a command prompt run msdtc -uninstall without the quotes.

1. Verify the DTC was uninstalled successfully by reviewing the application event log.
2. Open regedit and ensure the following registry keys have been deleted (they all may not be present):
   • HKEY_CLASSES_ROOT\CID
   • HKEY_CLASSES_ROOT\CID.Local for Windows 2008
   • HKEY_LOCAL_MACHINE\SOFTWARE\Microsoft\MSDTC
   • HKEY_LOCAL_MACHINE\SYSTEM\CurrentControlSet\Services\MSDTC
3. Reboot the Server
4. From a command prompt run msdtc -install without the quotes.
5. Verify the MSDTC was installed successfully by reviewing the application event log.
6. From a command prompt run msdtc -resetlog without the quotes.
7. In the Administrative tools, Services verify the Distributed Transaction Coordinator service is started and then change the properties of the service so the start up type is automatic.
8. Enable DTC network access if required.

For Reference below MSDN blog will be helpfull 

http://blogs.msdn.com/b/distributedservices/archive/2009/04/01/instructions-to-reinstall-the-microsoft-distributed-transaction-coordinator-msdtc-service.aspx

Thanks
Abhishek

• Marked as answer by Angie xuMicrosoft contingent staff, Moderator Tuesday, July 14, 2015 5:29 AM

Thank you everyone for your responses.