Currently we are wanting to disable the USB ports in front of all of our Dell OptiPlex 7010 machines. Is there a complex PowerShell Script for this out there?

You can disable USB port from Group policy method. You can restrict user to use USB port and apply via Group Policy method. solution and question already asked on tech net hope it also works for you

https://social.technet.microsoft.com/Forums/windowsserver/en-US/0be0c42b-950c-4a16-8be6-3f3a3d22e712/process-for-usb-port-blocking-via-active-directory-group-policy?forum=winserverGP