We have a win 2008 server and and are accessing it with Win Pro clients. All users can NOT open an MS Word document that are on a web based server. PDF fiels can be opened. Saving the Word document locally then opening it is OK and works. New users to the domain can open the files too; it is only exisiting users inside the firewall that can not open the Word docs....which leads us to think it is a corrupt profile. We are not using roaming profiles. It is odd that t affects all "old" users. We are using Office 2010; primalily MS Word. Recreating the user soleve sthe problem - meaning the user can open the MS Word docs from the web.Gregorio

Hello, you have file server and client cannot access or you have terminal server and in these terminal server users cannot open word files? you can change "default profile" folder take from another server. Best Regards. Fatih

Thanks Faith. No TS involved. Simply a website we access that contains several Word documents. Normally, a simple click asks us if we want to open the file - now it generates an error saying the file can not be opened. However, saving it to the local desktop allows you to open it....This was all working well for months then the error suddenly began appearing about two weeks ago. This (doc opening) works well from anywhwere outside the local firewall/domain. Gregorio

Hello, Did you change web server authentication or anything in web server 2 weeks ago?All clients cannot open files or some of them? By the way I prefer WSS or Sharepoint Server for this. This will the best way. (and WSS is free) Best Regards. Fatih

It sounds like Website permissions to me man. I would check and ensure with the authentication firstly. So check if its using anonymous access and from there you can check the shared directory thats hosting the files, and ensure whatever account the users use it has read permissions on that directory. Also check to see whether or not changing the Execute Permissions under Home Directory of the website doesnt change that, try set it on Scripts Only and see what it does. If its a normal website then its got to be the IIS permissions. One thing is bugging me though, the users can save the document which means they have read access with how they are accessing it, but the document is being read remotely.... Might even be Office settings that are causing the documents not to be opened. Edit: Just re-read your issues again and it must be something with AppData or along those lines in the Profile... MCP, MCSE, MCDST, MCSA, MCT, MCITP:EA, MCITP:CST, A+, N+, CTT+, MCTS, CBP

Hi, If you cannot open a specific Office file, the IE temporary cache file may be damaged or corrupted. To resolve this problem, please try to delete the temporary Internet files that Internet Explorer caches. If the problem continues, you may need to renew the old profiles. Hope it helps. Regards, Bruce