Hi Mohit,
You need to follow below steps:
1 Create a new host.
2 Create one host instance for the host.
3 Create receive and send handlers for each of the adapters used by the application.
4 Stop receive ports and wait until all running instances have finished processing.
5 Stop and unenlist the orchestrations.
6 Update all orchestrations to run on the new host.
7 Update all send ports to run on the new send handler for this host.
8 Update all receive locations to run on the new receive handler for this host.
9 Enlist and start orchestrations and start all receive locations and send ports.
Refer:
Configure BizTalk hosts per Application
Rachit