Hi I have just built a new Exchange 2007 server for a seperate office. The domain is mydomain.com Versions are Exchange 2007 SP2 and users have Outlook 2007. There is also another Accepted Domain of mydomain2.com. Roughly 3/4 users have just mydomain.com, but 1/4 users have mydomain2.com as their Primary SMTP address for their mailbox. For some reason, users with mydomain2.com as their Primary SMTP cannot set Out of Office messages within the Outlook client, they see a message saying Outlook cannot connect to the server. All other mail functionality appears to work fine. They can set the Out of Office in OWA though. Does Outlook/OWA have different ways of setting Out of Office? How can I find out where the error is?

Hi, Please check the following setting 1. Autodiscover Service settings Test-OutlookWebServices -ClientAccessServer "CASServer01" 2. permission settings on the EWS virtual directory. Set-WebServicesVirtualDirectory -identity "SERVERNAME\EWS (Default Web Site)" -externalurl "https://URL.domain/EWS/Exchange.asmx" -BasicAuthentication:$True 3. Logged on account(domain and username) should be the same as Exchange Server when you logon on via Outlook. Please remember to click Mark as Answer on the post that helps you, and to click Unmark as Answer if a marked post does not actually answer your question. This can be beneficial to other community members reading the thread.