I just uninstall Office 365 manually because the uninstall application didn't work. I already have again Office 365 but Outlook is not responding as the default e-mail client and I can not send files directly to the email application from explorer or any other app.

I just uninstall Office 365 manually because the uninstall application didn't work.

What exactly do you mean by "uninstall Office 365 manually because the uninstall application didn't work"

#1 - What happened when you tried to uninstall normally?

#2 - What steps exactly did you follow to "uninstall manually"?

Hi,

From the description, your Outlook is not recognized as the default email client while sending using commands in other applications, correct?

If this is the case, please first verify Outlook is set as default mail client according to the following steps:

1. Open Control Panel and search for Default Programs.

2. Select Set Default Programs link.

3. Choose Microsoft Outlook from the list of programs. Click "Set this program as default".

If Outlook has already been set as default, please try repairing your Office installation to see if it helps:

1. Open Control panel, Program and Features

2. Find and select your Office or Outlook installation

3. Click Change

4. Select Quick Repair then click the Repair button. (In older versions of Office, the option is called Repair.)

In addition, please also make sure you are not using Outlook 64-bit and 32-bit programs can't "see" 64-bit programs. If you are using 64-bit version of Office, check this registry key and create it if it does not exist:

HKEY_LOCAL_MACHINE\SOFTWARE\Wow6432Node\Microsoft\Office\15.0\Outlook
String: Bitness
Value: x64

For detailed information, please have a look at the following link:

http://www.slipstick.com/outlook/outlook-not-recognized-default-email-client

Please Note: Since the web site is not hosted by Microsoft, the link may change without notice. Microsoft does not guarantee the accuracy of this information.

Regards,

Steve Fan
TechNet Community Support