This all started when .Net Framework 1.1 was installed by mistake on the Exchange 2007 server.OWA/MobileAccess stoppet working after this. I successfully removed .net 1.1 but had to reinstalliis and Client Access Role to get things working. In the recomended removal process (another forum) the total removal of IIS was preferred.After reinstall of IIS and Exchange Client Access only "Exchweb" and "OWA" and RPC is present of the Exchange virtual directories. I suppose this is why i now am unable to use Outlook Anywhere.Does anyone know how i can regenerate the lost virtual directories to get this up?Server:Windows 2003 R2 x64 EnterpriseExchange 2007 Standard, This server has all the rolesthanks!

solved by running : Step 4: Re-create the IIS virtual directories to restore links with the Exchange 2007 Mailbox role If Exchange is configured to have the Mailbox role, re-create the virtual directories in IIS to restore the links to the Mailbox role. Important If Exchange is not configured to have the Mailbox role, skip this step.To re-create the virtual directories in IIS, follow these steps: 1. Start the Exchange Management Shell. To do this, click Start, point to All Programs, point to Microsoft Exchange Server 2007, and then click Exchange Management Shell. 2. Type the following commands. Press ENTER after you type each command. get-owavirtualdirectory -server server_name -DomainController dc_name | ? {$_.OwaVersion -eq "Exchange2003or2000"} | remove-owavirtualdirectory -DomainController dc_name new-OwaVirtualDirectory -OwaVersion "Exchange2003or2000" -VirtualDirectoryType "Mailboxes" -DomainController dc_name new-OwaVirtualDirectory -OwaVersion "Exchange2003or2000" -VirtualDirectoryType "Exadmin" -DomainController dc_name new-OwaVirtualDirectory -OwaVersion "Exchange2003or2000" -VirtualDirectoryType "PublicFolders" -DomainController dc_name new-OwaVirtualDirectory -OwaVersion "Exchange2003or2000" -VirtualDirectoryType "exchweb" -DomainController dc_nameNotes Replace server_name with the name of the Exchange 2007 server. Replace dc_name with the name of a domain controller.Note Alternatively, you can put these commands into a script file (.ps1) and then run them at the same time.Reboot and okfound in this articlehttp://support.microsoft.com/kb/320202/en-us