We use Exchange 2013 with mix of Outlook 2013 and outlook 2010 users. I have one user using Outlook 2010 that cannot set OOF replies in Outlook but can set them in OWA -get this error
I have tested Autodiscover with this user and all passes with same setting for working users. Does this seem to point to an Outllook problem - maybe profile or reinstall.? Any other test I can run to verify?