Hi,
Does the program call the CoCreateInstance function to create a 32-bit instance of Internet Explorer? If this is the case, please check if the following KB article applies:
https://support.microsoft.com/en-us/kb/2310259
This issue occurs because no 32-bit handler for the InternetExplorerMedium class identifier (CLSID) is registered.
An application calls the CoCreateInstance function to create a 32-bit instance of Internet Explorer 8 in a 64-bit version of Windows 7 or of Windows Server 2008 R2. This operation fails when there is no 32-bit handler for the
InternetExplorerMedium CLSID in the running operating system. In this scenario, the
CoCreateInstance function creates a 64-bit instance instead.
Since this question is more related to Internet Explorer, if you need further assistance on the issue, I'd recommend you post a new question to the forum for Internet Explorer:
https://social.technet.microsoft.com/Forums/ie/en-US/home?category=internetexplorer
The reason why we recommend posting appropriately is you will get the most qualified pool of respondents, and other partners who read the forums regularly can either share their
knowledge or learn from your interaction with us. Thank you for your understanding.
Steve Fan
TechNet Community Support