Hello! Had a question. I have 2 different email domains under Outlook. Right now I am having to copy and paste my signature depending on what email I am using. Is it possible to have it where outlook will auto populate the signature based on what email I choose to email from? Rather than have to copy and paste each time. 

Hi,

Which version of Outlook are you using?

We can set default signature for different account in the Signatures and Stationery dialog via clicking the Email Account drop-down list:

If I've misunderstood something, please feel free to let me know.

Regards,

Steve Fan
TechNet Community Support