We have a PowerPoint 2013 presentation where we put a OneNote notebook on one of the slides, which we'd like to open, but it appears to only be able to be double-clicked and opened when in editing mode, now when you're in Presenter View. 

Is there a way to get it to play without leaving the presentation view all the guests are watching?

Hey,

I am not sure than you can open one note in power point without leaving power point, try these steps may be this work for you

support.office.com/en-sg/article/OneNote-and-PowerPoint-Better-together-545a51f2-04bb-472f-b322-7018e590e5c5