Hi,
This Warning event indicates that the value specified for the Internet Information Services (IIS) setting referenced in the event description is not valid. The value has been changed to the default value. Microsoft Exchange ActiveSync will use the default settings until the next time that the server that is running Microsoft Exchange is restarted.
To make sure that this warning does not occur again, follow these steps to manually change the settings to the default settings:
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Start Internet Information Services (IIS) Manager.
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In the console tree, click Web Sites, and then click Default Web Site.
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Right-click Microsoft-Server-ActiveSync, and then click Properties.
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On the ASP.NET tab, click Edit Configuration.
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On the General tab, under Application settings, configure the setting specified in the event description to the default value.
Note You must restart Internet Information Services (IIS) by using the command iisreset/noforce for these changes to take effect.
Refer from