We have exchange 2007 / sp2 running on win 2003 r2 - backup exec version 11 running backups every night. been running successfully for about 2.5 years now, but the last three backups have returned this error:Job ended: Wednesday, December 16, 2009 at 12:20:33 AMCompleted status: FailedFinal error: 0xe0008488 - Access is denied.Final error category: Security ErrorsFor additional information regarding this error refer to link V-79-57344-33928Backup- \\EXCH07\Microsoft Information Store\First Storage Group Unable to complete the operation for the selected resource using the specified options. The following error was returned when opening the Exchange Database file: '-1018 There is a checksum error on a database page. 'Any ideas on a solution to this would be greatly appreciated. Thanks,Bill

http://support.microsoft.com/kb/314917Understanding and analyzing -1018, -1019, and -1022 Exchange database errors1018s are not good and typically indicate a hardware problem.Can you move mailboxes to another server? Any other errors in the logs?