We have kind of strange requirement, we have 3 Exchange Server and are in 3 different forests.

All users computers are joined to one single domain say ABC.local where all users gets authenticated.

Now we want to restrict cache mode configuring of Outlook for the Exchange which is installed in ABC.local domain. 

If we try to restrict it by Group Policy then other 2 forest exchange users also will not be able to configure cached mode. So not sure how to achieve this. 

But again in ABC.local also we need to have some exception where higher management should be excluded from this policy(they should be allowed to configure cached mode).

Can anyone one help me to achieve this scenario.

Thanks,
Vij

Group policy allows you to selectively apply or restrict application by OUs, groups or even individual users and computers.

Yes, but if i apply Group Policy then it will apply on one users Outlook where he can;t even configure other email domain account also with Cache mode. I want to restrict only one Exchange Server (abc.com) from Cache mode configuration. Same user should be able to configure all other account (xyz.com or 123.com) in his outlook with cached mode.

Hope you got my point.

Put all the users whose mailboxes are on abc.com and apply the GPO to that group.

What my understanding is if user A login to PC and if i apply the GPO, it will be effected on the Outlook. Which means the same user A will not be able to configure ABC.com domain in cached mode is it is very much possible. But the problem here is the same user need to configure other domain accounts in cache mode as well which is from different exchange servers xyz.com and 123.com. We dont want to restrict user A from configuring cache mode for other domian (xyz and 123.com).

If you can help me with little bit more detail on GPO how to achieve this scenario that would be helpful. 

GPOs can be enforced by user or by computer.

Hi,

According to your description, I understand that restrict Cache Mode only for user in abc.local domain and configure outlook with Exchange address(A@abc.com), however it not effect when configure outlook with other Exchange address(A@123.com or A@xyz.com, A account has linked mailbox in 123.com and xyz.com forest).
If I misunderstand your concern, please do not hesitate to let me know.

As far as I know, Exchange has no built-in function to disable cached mode for mailbox. We can disable the cached mode on Outlook side, or using Group Policy. For your reference: https://social.technet.microsoft.com/Forums/office/en-US/0a1ec2a3-a470-454f-8225-4db376f1a608/disable-cached-mode-via-script-for-outlook-2010?forum=outlook

For your particular situation, we might need customize GPO or script to archive this. Please contact Scripting for Exchange Server Team so that you can get more professional suggestion, please refer to:
https://technet.microsoft.com/en-us/scriptcenter/dd742246.aspx?f=255&MSPPError=-2147217396

Thanks