We are having a strange issue which has surfaced over the last 24 hours. I'm not sure what information you may need to help, so please ask and I'll get it. I work in our IT department, so I can find what info is needed. We have 1 DB server and 1 Web server for our environment. If you go to any site (My Site, entire site collection) to open a file (Word, Excel) to edit it, you can edit the body of the file, hit Save, and it updates the file as it should. If you open the same file, make edits to the body/content, but need to change the file name to something different, it fails to upload stating "Path cannot be found." It doesn't matter if the file is checked out first or not. You also cannot move files via Windows Explorer, it states that "File name is not valid or too long."... Occasionally with the failed upload docs that are stuck in the MS Office Uploader, you can tell it to Upload All and it will work, and other times it won't. This is environment wide, so it doesn't seem to be just one or two computers, it is all 150+ users with Office Pro Plus 2010. I ran some Wireshark packet captures, and when you open the file (read only or edit mode), after PROPFIND the next entry is an HTTP/1.1 401 Unauthorized NTLMSSP_CHALLENGE (text/html) entry. There's another PROPFIND, and after several lines an HTTP/1.1 207 Multi-Status message. Next PROPFIND there are two HTTP/1.1 404 Not Found messages...I did see a 409 error in there, so there's something up (obviously). I am just wondering if anyone has had this issue and can point us into the right direction. We have to do some server maintenance tonight, so we were going to restart our SP Database server and Web server, and attempt this: http://joranmarkx.wordpress.com/2011/11/28/cannot-upload-or-edit-document-in-sharepoint-20072010/ Again, anything that is needed from me please ask. Thank you! Ryan

Running the scripts in the link solved our issue.