I updated to Windows 10 and now my E. Drive is mssng and CD/DVD will not work.  All my games are gone also

More often than not when a device isn't working it is because the driver has become corrupted. Re-installing a fresh copy should help http://windows.microsoft.com/en-us/windows7/Update-a-driver-for-hardware-that-isnt-working-properly?SignedIn=1

http://captaindbg.com/how-to-update-drivers-on-windows-7/   (works on win 8 & win 10)

Please run a system file check (SFC) & DISM (if necessary) if you are on win 8 or higher
All instructions are in our Wiki article below...
Should you have any questions please ask us.

System file check (SFC) Scan and Repair System Files

elp_01

First, please check if the partition still there in Disk management.

If it can be seen, please right click to change or assign a driver letter to see if we can get this issue fix.

Also, you can check solution here in this thread: https://social.technet.microsoft.com/Forums/en-US/beb91d4d-e38a-46dd-adb7-48bfb4daa4ca/windows-10-upgrade-hard-drive-partition-lost?forum=win10itprosetup

For the CD/DVD drive issue, please reinstall the driver in device manager to check the results.