We have SSRS 2008 running on a web server thats externally accessible via a FQDN (i.e. site.domain.com). We have several web applications running on this web server including SharePoint and some .NET web applications, all of which are accessible without issue. For some reason, however, we can not access SSRS using the FQDN (i.e. http://site.domain.com/Reports) - when trying to do so we get 404 Not Found. If we access the site using the internal IP address (when we're inside our network of course - i.e. http://192.168.123.123/Reports) - it comes up fine and works as expected. Any thoughts as to what needs to be done to get this working with the domain name? Thanks a bunch!

Finally got this figured out. Changed the URL that was set to "All Unassigned" to "All Assigned" and things are working perfectly now.

Just wondering where you set this up. I have "All Assigned(Recommended)" under the IP Address of Web Service URL of the Reporting Service Configuration Manager. I am seeing such problem with a few user. Most of my user can access the server with FQDN. Thank you, BishowBisu2000