Hi There,

We have noticed that .NET Framework 2.0/3.5 is not working anymore post upgrade of OS from 2003 R2 to 2008. Because of this .NET dependent application also not working.

Unable to repait/reinstall/uninstall/clean-up .net framework post OS upgrade. 

Have anybody faced this issue? any suggestion how to fix this?

Thanks

After the upgrade I'd try running SUR tool

http://windows.microsoft.com/is-IS/windows7/What-is-the-System-Update-Readiness-Tool

then check %SYSTEMROOT%\Logs\CBS\CheckSUR.log for errors. Post complete if errors found.

Hi,

Did you run this server as application server?

If yes, according to the MS article:

You cannot migrate the Application Server role from Windows Server 2003 to Windows Server 2008. It was rebuilt for Windows Server 2008, and it includes default support for applications that are built with .NET Framework 3.0 components, such as Windows Communication Foundation (WCF), Windows Workflow Foundation (WF), and Windows Presentation Foundation (WPF). Application Server offers optional role services that activate features in Windows Server 2008 (such as Windows Process Activation Service (WAS) support for non-HTTP protocols, TCP Port Sharing, and support for IIS 7.0). If you upgrade your server to Windows Server 2008 from Windows Server 2003 or an earlier operating system, and you want to use the capabilities of the Application Server role, you must reinstall the Application Server role by using the Add Roles Wizard in Server Manager. If you configure Windows Server 2008 with the correct application services by using the Add Roles Wizard, your applications will work correctly after you move them from Windows Server 2003 to Windows Server 2008.

https://technet.microsoft.com/en-us/library/cc755199%28v=ws.10%29.aspx?f=255&MSPPError=-2147217396

Regards.